Clinical Phenomenology of Bipolar Disorder With Substance Use Disorders: A Systematic Review - PubMed
2 hours ago
- #Bipolar Disorder
- #Comorbidity
- #Substance Use Disorders
- Bipolar disorder (BD) frequently co-occurs with substance use disorders (SUDs), worsening clinical outcomes.
- Cannabis use disorder (CUD) in BD is associated with increased manic episodes, rapid cycling, psychosis, and earlier onset.
- Alcohol use disorder (AUD) in BD is linked to worse depression outcomes and increased suicidality.
- Other SUDs (cocaine, tobacco, opioids, methamphetamine) show links to increased suicidality, hospitalizations, and medication nonadherence.
- Research gaps exist for non-alcohol and non-cannabis SUDs, highlighting the need for more rigorous studies.