Incidence and Risk Factors for Progression from Pre-COPD to COPD: A Systematic Review and Meta‑analysis - PubMed
9 hours ago
- #COPD
- #respiratory health
- #meta-analysis
- Pre-COPD refers to individuals not meeting traditional COPD criteria but showing symptoms, abnormal lung function, or imaging changes.
- A systematic review and meta-analysis found a 20% pooled incidence of progression from pre-COPD to COPD.
- Key risk factors for progression include PRISm (OR=2.92), age (OR=1.09), smoking history (OR=4.08, HR=2.21), NOCB (OR=2.07, HR=2.46), and asthma (OR=2.50).
- The study suggests integrating these risk factors into clinical tools to identify high-risk individuals for targeted interventions.