Saturated Fat Restriction for Cardiovascular Disease Prevention
17 hours ago
- #cardiovascular disease
- #saturated fat
- #meta-analysis
- Systematic review and meta-analysis investigates the efficacy of saturated fat reduction in preventing cardiovascular diseases and mortality.
- Nine randomized controlled trials with 13,532 participants were analyzed, including primary and secondary prevention studies.
- No significant differences found in cardiovascular mortality, all-cause mortality, myocardial infarction, or coronary artery events between intervention and control groups.
- Impact of stroke could not be evaluated due to limited reported cases.
- Conclusions suggest that current evidence does not support recommending saturated fat reduction for cardiovascular disease prevention.
- Authors call for further clinical trials to evaluate effects under optimal medical care, including statin use.
- Study registered with the International Prospective Register of Systematic Reviews (CRD42023428498).