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Buffered versus non-buffered lidocaine with epinephrine for subcutaneous implantable venous access devices insertion reduces pain: A randomized trial - PubMed

3 days ago
  • #Vascular Access
  • #Anesthesia
  • #Pain Management
  • The study compared buffered (pH=7.33) and non-buffered (pH=3.50) lidocaine with epinephrine for pain reduction during Port-a-Cath insertion in cancer patients.
  • Buffered lidocaine significantly reduced pain during local anesthesia infiltration (15.7 ± 7.6 mm vs. 46.9 ± 12.3 mm, p < 0.001).
  • Patient satisfaction was higher with buffered lidocaine (95.75 ± 8 mm vs. 70.2 ± 20.1 mm, p < 0.001).
  • Sensory block onset time was shorter with buffered lidocaine (3.25 ± 1.3 min vs. 5.5 ± 1.3 min, p < 0.001).
  • Conclusion: Alkalinizing lidocaine with epinephrine improves anesthesia quality and patient satisfaction during Port-a-Cath placement.