The HONEST Cohort Study: Rationale and Design of a Nationwide Subcutaneous Implantable Cardioverter-Defibrillator Cohort - PubMed
4 hours ago
- #S-ICD
- #Real-World Evidence
- #Sudden Cardiac Death
- The HONEST study is a nationwide cohort evaluating subcutaneous implantable cardioverter-defibrillator (S-ICD) recipients in France.
- It aims to provide real-world data to reduce complications and refine strategies for preventing sudden cardiac death.
- The study included 4,924 patients (77% male, average age 49.9 years) from October 2012 to December 2019.
- Endpoints are centrally adjudicated, and the cohort represents 98.2% of all S-ICD implantations during the period in France.
- Funding comes from French cardiology societies and research institutes, with no involvement from the device manufacturer.