The Molecular Basis of Long Covid Brain Fog
9 hours ago
- #Long COVID
- #Brain Fog
- #AMPA Receptors
- Researchers from Japan used a novel imaging technique to visualize AMPA receptors in the brains of Long COVID patients.
- Higher AMPA receptor density was found in Long COVID patients and correlated with the severity of cognitive symptoms like brain fog.
- The study suggests AMPA receptors could serve as diagnostic biomarkers and therapeutic targets for Long COVID brain fog.
- The novel imaging method, [11C]K-2 AMPAR PET, distinguished patients from healthy controls with high accuracy (100% sensitivity, 91% specificity).
- Inflammatory markers were also correlated with AMPAR levels, indicating a possible link between inflammation and cognitive symptoms.
- The findings could lead to new diagnostic tools and treatments, such as drugs that suppress AMPAR activity.
- The study highlights Long COVID brain fog as a legitimate clinical condition needing further research and therapeutic development.