Comparative Effectiveness of Pharmacological and Non-pharmacological Therapies for ADHD: A Systematic Review and Meta-analysis of Randomized Controlled Trials (2008-2023) - PubMed
2 days ago
- #treatment
- #ADHD
- #meta-analysis
- ADHD is a neurodevelopmental disorder affecting attention, impulse control, and hyperactivity.
- Stimulant medications like methylphenidate and amphetamines are effective but have side effects such as insomnia and cardiovascular risks.
- Non-pharmacological treatments include behavioral therapy, dietary changes, and neurofeedback, but their effectiveness is uncertain.
- A systematic review and meta-analysis compared pharmacological and non-pharmacological ADHD treatments from 2008-2023.
- 18 RCTs were analyzed, showing stimulants consistently reduce ADHD symptoms but have modest effects on academic performance.
- Non-stimulants like viloxazine and guanfacine showed modest improvements, while iron and omega-3 supplements had pronounced benefits.
- Behavioral and cognitive interventions had inconsistent results, while combined approaches were more effective for social and functional outcomes.
- The study concludes that individualized treatment combining pharmacological and non-pharmacological approaches yields the best ADHD management.