The Italian Society of Urology Statement on focal therapy for localized prostate cancer - PubMed
5 days ago
- #focal therapy
- #urology
- #prostate cancer
- Focal therapy (FT) is a promising strategy for localized prostate cancer (PCa) management.
- Patient selection for FT must be stringent due to limited long-term evidence and PCa heterogeneity.
- Ideal FT candidates have unilateral, localized, mpMRI-visible lesions, ISUP Grade Group 2, and >10 years life expectancy.
- FT energy sources (cryotherapy, HIFU, irreversible electroporation, laser ablation) offer comparable outcomes.
- Energy modality choice depends on tumor location, physician expertise, and technology availability.
- FT follow-up includes PSA monitoring and mpMRI; biopsy is not routine except for new FT programs.
- The SIU position paper provides FT recommendations for patient selection, treatment, and follow-up.