Cationic hydrogel with sustained lubrication and anti-calcification for osteoarthritis therapy - PubMed
4 hours ago
- #hydrogel
- #calcification
- #osteoarthritis
- Novel cationic hydrogel (mCS/Lys) designed for osteoarthritis therapy.
- Dual functionality: enhances lubrication and inhibits pathological calcification.
- Structural modifications create a brush-like architecture for better performance.
- Outperforms hyaluronic acid in duration and therapeutic efficacy.
- Effective in murine models: inhibits calcification, alleviates pain, repairs cartilage.
- Offers a holistic, enduring treatment approach compared to single-target methods.