Integrative Dermatology for Longevity: The Synergy of Topical and Internal Approaches - PubMed
19 hours ago
- #Integrative Dermatology
- #Skin Aging
- #Longevity
- Skin aging is influenced by both intrinsic biological decline and extrinsic factors like UV radiation, pollution, stress, and lifestyle, which cause molecular and structural damage.
- An integrative 'In and Out' approach combines topical treatments (e.g., retinoids, peptides, antioxidants, exosomes) with internal nutraceuticals (e.g., NAD+ precursors, collagen peptides, polyphenols, microbiome modulators) to target aging hallmarks such as oxidative stress, inflammation, and epigenetic changes.
- This dual-modality model aims to promote skin regeneration, improve aesthetic and functional outcomes, and contribute to health span optimization, supported by tools like skin aging clocks, biomarker personalization, and AI-guided interventions.
- Personalized strategies that integrate diagnostic tools, lifestyle coaching, and tracking technologies enable adaptive and dynamic approaches to dermatology, redefining its role in longevity.