Reinforced biotubes as readily available and regenerative vascular grafts - PubMed
4 hours ago
- #regenerative medicine
- #tissue engineering
- #vascular grafts
- Reinforced biotubes (dPB) combine in vivo bioengineering and decellularization for vascular grafts.
- dPB exhibit mechanical strength, anti-kinking, puncture resistance, and long-term storage at 4°C.
- Loose, porous microstructure and immunomodulatory properties promote rapid recellularization and M2 macrophage polarization.
- Successful applications in porcine, canine, and ovine models show high patency without complications.
- dPB offer a readily available, pro-regenerative solution for patients lacking autologous vessels.