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A sorghum pangenome reference improves global crop trait discovery - PubMed

a day ago
  • #pangenome
  • #crop breeding
  • #sorghum
  • A sorghum pangenome reference was constructed with 33 members to improve crop trait discovery.
  • A diversity panel of 1,984 sorghum cultivars and landraces was analyzed to explore genetic diversity and adaptation.
  • Multiple nested and deeply diverged structural variants were found in the domestication gene SHATTERING1, indicating a multicentric origin of sorghum.
  • Landscape genomics revealed how gene flow and secondary contact created a complex genetic mosaic in breeding networks.
  • Biosynthetic gene cluster structural variation was linked to phenotypic leaf concentration of the cyanogenic glucoside dhurrin.
  • The study provides a framework for accelerating breeding and trait discovery in sorghum and other crops.