Research Progress on the Application and Mechanisms of Baihe Dihuang Decoction in Major Depressive Disorder - PubMed
4 hours ago
- #Pharmacological Mechanisms
- #Depression Treatment
- #Traditional Chinese Medicine
- Baihe Dihuang Decoction (BHDH) shows promise as an adjunct therapy for Major Depressive Disorder (MDD), improving clinical response rates and reducing depression scale scores.
- The antidepressant mechanisms of BHDH involve multiple pathways, including modulation of monoaminergic neurotransmission, inhibition of neuroinflammation, and regulation of the hypothalamic-pituitary-adrenal axis.
- Further research is needed to validate BHDH's efficacy as a monotherapy and its long-term safety profile through high-quality clinical trials.