Preceding Infections and Coagulation Biomarkers in Early-Onset Cryptogenic Ischemic Stroke - PubMed
3 hours ago
- #ischemic stroke
- #coagulation biomarkers
- #infection
- Recent infections within the preceding week are associated with a 2.6-fold higher odds of early-onset cryptogenic ischemic stroke (CIS).
- VWF (von Willebrand Factor) activity is significantly higher in CIS cases compared to controls, especially in those with recent infections.
- Stratified analyses show that VWF and factor VIII levels are more strongly linked to CIS in individuals with recent infections or fever.
- The study suggests infection-related thromboinflammatory mechanisms may play a role in CIS, warranting further research into preventive measures.