The Male Biological Clock
a day ago
- #male fertility
- #aging
- #sperm health
- Men's fertility peaks in late twenties to early thirties and declines after 40, with DNA integrity being particularly vulnerable.
- Sperm DNA fragmentation doubles from age 25 to 55, making conception harder and increasing miscarriage risks.
- Oxidative stress is the main biological mechanism behind sperm aging, causing DNA damage and reduced antioxidant defenses.
- Lifestyle factors like obesity, smoking, and alcohol significantly impact sperm quality, while a Mediterranean diet and moderate exercise can improve it.
- Advanced paternal age (40+) is linked to higher risks of preterm birth, infant seizures, autism, and schizophrenia in offspring.
- Men over 40 should consider sperm cryopreservation and lifestyle changes to improve fertility outcomes.
- Sperm regeneration takes 74 days, so lifestyle interventions require at least three months to show results.