Frailty and Recurrent Cardiovascular Events in Patients With Obstructive Sleep Apnoea: The SAVE Study - PubMed
5 hours ago
- #cardiovascular disease
- #obstructive sleep apnoea
- #frailty
- Frailty is common in patients with cardiovascular disease (CVD) and obstructive sleep apnoea (OSA).
- The SAVE study investigated whether frailty modifies the risk of recurrent cardiovascular events in patients with OSA and established CVD.
- Participants were categorized into nonfrail, moderately frail, and severely frail groups using the Rockwood frailty index (FI).
- Severe frailty was associated with increased risks of composite cardiovascular events, stroke, hospitalization for unstable angina, all-cause mortality, and CVD death.
- There was no significant difference in CPAP treatment adherence or its effect on cardiovascular events across frailty groups.
- Higher frailty index was linked to significantly higher risk of recurrent cardiovascular events in OSA patients with CVD.