Sex-specific association between osteoporosis and cataracts: UK Biobank and Hong Kong Osteoporosis Study - PubMed
4 hours ago
- #osteoporosis
- #bone-density
- #cataracts
- Osteoporosis is associated with a higher risk of age-related cataracts, particularly in women.
- Two large prospective cohorts from the UK and Hong Kong were studied, with median follow-ups of 13.5 and 18.5 years respectively.
- Participants with lower bone mineral density (BMD) T-scores had a higher risk of developing cataracts.
- Five circulating proteins (MEPE, GDF15, TCN2, CDCP1, SIGLEC1) were identified as potential mediators linking osteoporosis to cataract development.
- The study highlights the importance of integrated care for patients with osteoporosis and cataracts, suggesting timely ophthalmic evaluation for those with low BMD.