Associations of Lichen Sclerosus With Autoimmune Diseases: A Systematic Review and Meta-Analysis - PubMed
3 hours ago
- #autoimmune diseases
- #lichen sclerosus
- #meta-analysis
- Lichen sclerosus (LS) is associated with several autoimmune diseases, including dermatologic conditions like morphoea, lichen planus, vitiligo, alopecia areata, and psoriasis.
- LS also shows associations with autoimmune thyroid diseases and gastrointestinal disorders such as coeliac disease and Crohn's disease.
- No significant associations were found between LS and systemic lupus erythematosus, type 1 diabetes mellitus, ulcerative colitis, rheumatoid arthritis, or pernicious anaemia.
- The study underscores the importance of screening, multidisciplinary care, and long-term monitoring for optimal management of LS patients with associated autoimmune conditions.
- The research involved a systematic review and meta-analysis of 11 observational studies, utilizing a random-effects model for data synthesis.