Prognostic Role of Inflammatory Blood Cell Ratios in Glioblastoma Patients: Insights from a Single-institution Study - PubMed
3 hours ago
- #inflammatory markers
- #glioblastoma
- #prognosis
- Glioblastoma multiforme (GBM) is an aggressive brain tumor with poor prognosis despite treatment.
- Study analyzed 74 GBM patients treated with radiotherapy and temozolomide from 2014-2024.
- Inflammatory markers (NLR, MLR, SII, SIRI) were assessed for prognostic significance.
- Elevated NLR, MLR, SII, and SIRI correlated with significantly worse overall survival (OS).
- Median OS was shorter in patients with high NLR (14 vs. 21 months), MLR (13 vs. 16 months), SII (14 vs. 20 months), and SIRI (13 vs. 20 months).
- No significant link found between inflammatory markers and MGMT promoter methylation status.
- Inflammatory markers could aid in risk stratification and personalized treatment planning for GBM patients.