Prognostic value of hemodynamic indices prior to tMCS explantation: An analysis from the Cardiogenic Shock Working Group - PubMed
3 days ago
- #cardiogenic shock
- #mechanical circulatory support
- #hemodynamic indices
- Hemodynamic indices like BPRI, OPP, API, and mAPI were evaluated for predicting outcomes in cardiogenic shock patients on tMCS.
- BPRI showed the highest prognostic accuracy for in-hospital mortality (AUC 0.786) and native heart survival (AUC 0.747).
- Survivors demonstrated significant BPRI improvement (8.4 to 18.2), while non-survivors showed stagnation (4.7 to 5.2).
- Each 10-point increase in BPRI was associated with a 46% reduction in mortality (OR 0.54, 95% CI 0.42-0.68, P<0.001).
- BPRI's predictive value was consistent across different tMCS platforms, including Impella and IABP.
- The study highlights the need for standardized hemodynamic-guided weaning criteria in cardiogenic shock patients.