Aging and increased cancer risk: exploring the potential of LE8 score to mitigate risk - PubMed
3 hours ago
- #aging
- #cancer risk
- #LE8 score
- Aging is significantly associated with increased overall cancer risk.
- Four aging markers (KDM, PhenoAge, leukocyte telomere length, and chronological age) were used to assess biological aging.
- Elevated aging measures correlate with higher risks for seven specific cancers, including esophageal, colorectal, and pancreatic cancers.
- Life's Essential 8 (LE8) score interacts with PhenoAge to influence lung cancer risk.
- Higher LE8 scores are linked to reduced cancer risk in individuals with biological aging, particularly for esophageal, gastric, breast, and uterine cancers.