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Designing a machine learning model for predicting cardiovascular events using the triglyceride-glucose index: a cohort study - PubMed

3 hours ago
  • #TyG Index
  • #Machine Learning
  • #Cardiovascular Disease
  • Cardiovascular diseases (CVD) are the leading cause of death in developing countries.
  • Early detection of high-risk CVD patients could reduce mortality.
  • The study explores the triglyceride-glucose (TyG) index's effectiveness in predicting CVD events using machine learning.
  • Data from the MASHAD cohort was used, with patients monitored for over ten years.
  • Eleven machine learning models were evaluated, including MLP and AdaBoost classifier.
  • CVD event prevalence was 10.9%, with an average age of 48.08 years and 60% female participants.
  • The mean TyG index was 8.59 ± 0.66.
  • MLP and AdaBoost models showed the highest predictive accuracy (ROC-AUC scores of 0.77 and 0.766).
  • The TyG index was the fourth most significant predictor in MLP and AdaBoost models.
  • Incorporating the TyG index could enhance CVD risk prediction accuracy, especially in developing countries.