Outcomes of SARS-CoV-2 infection post-solid organ transplantation in the cystic fibrosis population - PubMed
a day ago
- #Cystic Fibrosis
- #Transplantation
- #COVID-19
- Study examines outcomes of SARS-CoV-2 infection in cystic fibrosis (CF) patients post-solid organ transplantation.
- Retrospective international cohort study involving 526 SARS-CoV-2 infections from 19 countries.
- Median age at infection was 36 years, with median time since transplant at 5.8 years.
- Timing of transplant relative to infection did not significantly affect hospitalization or death risk.
- Higher baseline ppFEV1 was associated with lower odds of severe outcomes (death or hospitalization).
- Lung function trajectory did not significantly change in the year following SARS-CoV-2 infection.
- Patients with more severe lung disease were at higher risk for worse outcomes.