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EffectS of Lifestyle Interventions in Older PEople With Obesity (Effective SLOPE): a Systematic Review With Network Meta-Analyses - PubMed

3 hours ago
  • #older-adults
  • #lifestyle-interventions
  • #obesity
  • Lifestyle interventions combining nutrition, exercise, and behavior change (NUT+EX+BCI) improve physical function in older adults with obesity, based on high certainty evidence.
  • NUT+EX+BCI may reduce body and fat mass without significantly harming fat-free mass or bone mineral density, though the evidence is very uncertain.
  • Other single or combined interventions may be effective, but effects are often imprecise; data on psychosocial outcomes, quality of life, and health events are insufficient or too heterogeneous for clear conclusions.
  • Further research is needed, particularly in frail populations and on patient-relevant outcomes, to strengthen the evidence base for obesity management in older adults.