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Which quadruple therapy should be prescribed as first-line treatment for Helicobacter pylori infection? Results of a prospective study comparing concomitant and bismuth therapy - PubMed

4 hours ago
  • #antibiotic resistance
  • #quadruple therapy
  • #Helicobacter pylori
  • Study compares two quadruple therapies for H. pylori infection: concomitant (QC-14) and bismuth-based (QB-10).
  • Both therapies showed similar eradication rates: 79.5% for QB-10 and 76.1% for QC-14.
  • Adverse events were comparable, with diarrhea more frequent in QC-14 and discolored stools only in QB-10.
  • Adherence rates were high (>93%) in both groups.
  • The study suggests that either therapy is effective, with choice depending on local resistance, cost, and patient factors.