Associations Between Albumin-Corrected Anion Gap and Mortality in Heart Failure Patients with Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study - PubMed
3 hours ago
- #chronic obstructive pulmonary disease
- #albumin-corrected anion gap
- #heart failure
- The study examined the association between albumin-corrected anion gap (ACAG) and mortality in heart failure patients with chronic obstructive pulmonary disease (COPD) using a retrospective cohort from the MIMIC-IV database.
- Higher ACAG levels were significantly linked to increased in-hospital and 30-day mortality, with the highest ACAG group showing hazard ratios of 2.04 and 1.83, respectively, compared to the lowest group.
- ACAG demonstrated superior predictive ability for mortality compared to anion gap and albumin alone, as shown by ROC analysis with an AUC of 0.693 for in-hospital mortality.
- The findings suggest ACAG is a potential prognostic predictor for risk stratification in this patient population, though further prospective studies are needed to confirm the results.