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AI-driven body composition atlas reveals its association with NSCLC immunotherapy outcome and molecular background: a multicenter study - PubMed

3 hours ago
  • #Gender Differences
  • #AI Body Composition
  • #NSCLC Immunotherapy
  • AI-based deep learning extracted 92 body composition parameters from CT scans in 2,132 NSCLC patients.
  • Higher intermuscular fat volume in males linked to better survival and enhanced immune activity in CD8+ T and NK cells.
  • T12 subcutaneous fat density in females associated with survival and M1 macrophage polarization, showing gender-specific effects.