Ten-year medication-free remission of type 2 diabetes in a South Asian male using a culturally adapted low-carbohydrate diet: an N-of-1 longitudinal study - PubMed
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- #low-carbohydrate diet
- #South Asian health
- #type 2 diabetes remission
- A South Asian male achieved 10-year medication-free remission of type 2 diabetes using a culturally adapted low-carbohydrate diet.
- The study followed a 49-year-old male with new-onset T2D (HbA1c 7.2%) through phased carbohydrate restriction (~100 g/day initially, <30 g/day for ketosis, then ~100 g/day for stabilization).
- Key outcomes included sustained HbA1c levels (4.7–5.3%), improved glucose control (>90% time-in-range), reduced Lp(a) (43.4 → 25.3 mg/dL), and stable cardiometabolic markers (CAC score 0, no stenosis in CIMT).
- The diet was well-tolerated with no deterioration in bone density, liver/renal function, or ophthalmic health over 10 years.
- Findings suggest moderate carbohydrate restriction (~100 g/day) may be a viable long-term strategy for metabolically obese normal-weight (MONW) South Asians, though broader validation is needed.