Calibrating the RT-cGAS-STING axis to drive cold-to-hot tumor transformation: mechanistic foundations and translational strategies for combination with immunotherapy - PubMed
4 days ago
- #cGAS-STING Pathway
- #Tumor Transformation
- #Immunotherapy
- The article discusses calibrating the RT-cGAS-STING axis to transform cold tumors into hot tumors.
- It explores mechanistic foundations and translational strategies for combining this approach with immunotherapy.
- Keywords include Cold-to-hot tumor transformation, Immune checkpoint inhibitors, and cGAS-STING pathway.
- The authors declare no competing interests.
- References include studies on hot and cold tumors, the abscopal effect, and the cGAS-STING pathway in radiation therapy.