Prognostic factors in combined pulmonary fibrosis and emphysema: a systematic review and meta-analysis - PubMed
7 hours ago
- #CPFE
- #prognostic factors
- #meta-analysis
- Combined pulmonary fibrosis and emphysema (CPFE) is associated with high mortality and poor prognosis.
- A systematic review and meta-analysis identified prognostic factors for CPFE, including age, smoking history, lung cancer, DLCO, DLCO%pred, CPI increase, and UIP pattern on HRCT.
- Lung cancer was also identified as a prognostic factor for acute exacerbation in CPFE patients.
- The study included 14 studies with 1,874 patients, with meta-analysis conducted on 10 studies involving 1,471 patients.
- Conclusions suggest these factors may inform clinical management, but further research is needed due to limited study quality and quantity.