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Blepharoclonus - a novel phenotypic association with a VAC14 variant - PubMed

5 hours ago
  • #NBIA disorders
  • #Blepharoclonus
  • #VAC14
  • Blepharoclonus is defined as brief clonic contractions of the bilateral orbicularis oculi muscles upon voluntary eye closure.
  • NBIA disorders such as PKAN, PLAN, and Kufor Rakeb disease have been associated with blepharoclonus.
  • A VAC14 variant is now identified as a novel phenotypic association with blepharoclonus, expanding the phenotype spectrum.