Gaps and Strategies for Management of Sepsis in Low-Resource Settings: Expert Consensus Statements Using a Delphi Method - PubMed
4 hours ago
- #low-resource-settings
- #sepsis-management
- #delphi-method
- 80% of sepsis cases occur in low-resource settings (LRS), where limited resources hinder guideline implementation.
- An international panel of 20 sepsis experts used the Delphi method to address gaps in sepsis care in LRS.
- The study reviewed 8865 studies, with 155 included, focusing on the 'sepsis chain of survival' framework.
- Consensus was achieved for 58 of 62 clinical practice statements after eight survey rounds.
- The statements guide sepsis prevention, early recognition, and management in LRS, from first response to post-sepsis care.
- There is a significant lack of high-quality evidence for sepsis care improvements in LRS.
- The clinical practice statements complement existing international guidelines and aim to support immediate care and future research in LRS.