Epidemiological trends and cross-country inequalities in the global burden of Alzheimer's disease and other dementias in postmenopausal women from 1990 to 2021 - PubMed
3 hours ago
- #Alzheimer's disease
- #global health inequalities
- #postmenopausal women
- The study evaluates the global burden of Alzheimer's disease and other dementias (ADOD) in postmenopausal women from 1990 to 2021, projecting trends to 2050.
- Key metrics include age-standardized rates (ASRs) for prevalence, incidence, mortality, and disability-adjusted life-years (DALYs), with East Asia showing the highest prevalence and incidence, and Central Sub-Saharan Africa the highest mortality and DALYs.
- Population growth (82.07%) and aging (12.48%) were the main drivers of increased DALYs globally from 1990 to 2021.
- Socio-demographic index (SDI)-related inequalities widened, with higher SDI countries bearing a disproportionately higher ADOD burden.
- Projections to 2050 indicate continued increases in ADOD burden, with high fasting plasma glucose identified as the leading risk factor.
- The findings emphasize the need for proactive prevention strategies, including targeted health policies and glucose control, to address the growing ADOD burden in postmenopausal women.