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The Intestinal microenvironment and Disorders of Gut-Brain Interactions - PubMed

4 days ago
  • #gut-brain axis
  • #microbiome
  • #DGBI
  • The intestinal microenvironment plays a significant role in Disorders of Gut-Brain Interaction (DGBI).
  • Food's role in DGBI-related symptoms has gained attention, but no specific microbial signature has been identified due to confounding factors.
  • The gut barrier, immune system, and enteroendocrine systems are crucial for signal transmission from the lumen to the host.
  • The microbiome-gut-brain axis concept explains symptom generation in DGBI, leading to new diagnostic and therapeutic approaches.
  • Recent research highlights the importance of luminal and enteric phenomena in DGBI.