Neurotoxicity of immune checkpoint inhibitors: a retrospective pharmacovigilance study using FAERS database - PubMed
3 hours ago
- #Pharmacovigilance
- #Neurotoxicity
- #Immune checkpoint inhibitors
- This study uses FAERS data to investigate neurotoxicity associated with immune checkpoint inhibitors (ICIs).
- Key neurological adverse events include encephalitis, encephalopathy, myasthenia gravis, and peripheral neuropathy.
- The median onset time is 30 days, with serious reports comprising 91.23% of cases, primarily in males aged 67.
- Findings highlight distinct neurological risks by ICI type and underscore the need for early recognition and management.