Arterial Endothelial Deletion of Alk1 Causes Severe Nosebleed by Impairing Nasal Smooth Muscle Cells - PubMed
7 hours ago
- #Alk1
- #smooth muscle cells
- #nosebleed
- Arterial endothelial deletion of Alk1 leads to severe nosebleeds.
- The study identifies impairment of nasal smooth muscle cells as the cause.
- Research conducted using mice models with tamoxifen-induced deletion.
- Findings relevant to hereditary hemorrhagic telangiectasia (HHT).
- Published in Circulation Research with PMID: 41822968 and DOI: 10.1161/CIRCRESAHA.125.327065.