Bacteriophage-mediated gut microbiota regulation: a bibliometric landscape analysis (2005-2024) - PubMed
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- #bibliometric analysis
- #bacteriophage
- #gut microbiota
- Systematic evaluation of bacteriophage-mediated gut microbiota regulation research from 2005 to 2024.
- Bibliometric analysis using CiteSpace, VOSviewer, and R-bibliometrix to map trends, collaborations, and research hotspots.
- Publication trends show a peak of 355 articles in 2022, with the US and China as main contributors.
- University College Cork and San Diego State University are core research institutions; Colin Hill is the most influential author.
- Frontiers in Microbiology published the most papers; Microbiome and Nature Communications are high-impact platforms.
- Research focus shifted from bacteriophage-bacterial interaction to 'bacteriophage-microbiota-host health' relationships.
- Recent core directions include short-chain fatty acids, microbiota disorders, and clinical interventions.
- 16 clinical trials included, with 14 based on moderate to high-quality evidence, indicating progression to intervention verification.
- Future research should focus on molecular mechanisms, standardized frameworks, and large-scale clinical trials for clinical application.