Age-related associations between the CALLY index and advanced cardiovascular-kidney-metabolic (CKM) syndrome: Insights from NHANES population data - PubMed
4 hours ago
- #CKM syndrome
- #NHANES
- #CALLY index
- The study explores the relationship between the CALLY index and advanced cardiovascular-kidney-metabolic (CKM) syndrome using NHANES data.
- The CALLY index, which combines C-reactive protein, albumin, and lymphocyte count, serves as a biomarker reflecting inflammation, nutrition, and immune function.
- Higher CALLY index values are associated with a lower likelihood of advanced CKM syndrome, with a 21% lower odds for those in the top tertile compared to the bottom.
- A threshold effect was noted in individuals under 60 years, where protective effects increased below a CALLY value of 455 units.
- The findings suggest the CALLY index could be useful for early detection and targeted interventions, especially in younger adults.
- Further validation through prospective studies is recommended to confirm these associations.