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Disturbing dreams and dementia incidence across diverse cohort studies: A COSMIC collaboration study - PubMed

4 hours ago
  • #sleep-disorders
  • #Alzheimer's-disease
  • #dementia
  • Distressing dreams were previously linked to all-cause dementia in older, predominantly white US men.
  • This study investigated the association between disturbing dreams (nightmares and bad dreams) and dementia incidence in a diverse international cohort aged 60-89.
  • Data from six longitudinal studies across Brazil, China, France, Italy, South Korea, and Taiwan (n=10,238, 42.5% men) were analyzed.
  • 24.2% of participants reported disturbing dreams, with all-cause dementia and Alzheimer's disease (AD) incidence rates of 10.8 and 5.3 per 1000 person-years, respectively.
  • In fully adjusted analyses, disturbing dreams were associated with increased all-cause dementia incidence among 60-69-year-olds (HR 3.93, 95% CI 1.32-11.67).
  • Weekly disturbing dreams were linked to AD only in men (HR 3.59, 95% CI 1.44-8.96).
  • No significant associations were found for older individuals.
  • The study suggests potential links between disturbing dreams and dementia in younger seniors and AD in men, but underlying mechanisms remain unclear.