Macrophage heterogeneity and plasticity: mechanism and therapeutics - PubMed
5 days ago
- #plasticity
- #heterogeneity
- #macrophage
- Macrophages regulate immune responses in inflammation and cancer.
- Macrophages can switch functional states based on microenvironment stimuli.
- Single-cell technologies and immunoinformatics help study macrophage states.
- Macrophage heterogeneity and plasticity are key in acute/chronic inflammation and cancer.
- Molecular mechanisms behind macrophage state transitions are highlighted.
- A conceptual framework for targeting macrophages pharmacologically is proposed.