Heparin Anticoagulant Therapy and Its Monitoring - PubMed
7 hours ago
- #monitoring
- #heparin
- #anticoagulation
- Heparin is a key parenteral anticoagulant used in acute and chronic care.
- The review covers clinical indications and dosing of unfractionated heparin (UFH) and low-molecular-weight heparin (LMWH).
- Laboratory monitoring methods include APTT, anti-Xa, ACT, and viscoelastic testing, with attention to pitfalls and interferences.
- Specific populations, heparin resistance, heparin-induced thrombocytopenia (HIT), and reversal strategies are discussed.
- Future research focuses on harmonizing therapeutic ranges, reducing assay interference, and monitoring in ECMO, pregnancy, and cardiac surgery.