The spatiotemporal dynamics of MAMs: mechanisms, pathologies, and therapeutic rewiring - PubMed
4 days ago
- #MAMs
- #Therapeutics
- #Mitochondria
- The article reviews the spatiotemporal dynamics of Mitochondria-Associated Membranes (MAMs), focusing on their mechanisms, associated pathologies, and potential therapeutic rewiring.
- Key pathologies linked to MAMs include cancer, diabetes, kidney disease, and neurodegenerative diseases.
- The article highlights the importance of MAMs in cellular functions such as ER stress response and mitochondrial lipid metabolism.
- Recent studies cited explore inter-organelle membrane contact sites and their roles in health and disease.
- The article does not involve any human or animal studies, as it is a review, and the authors declare no competing interests.