Interactions of SARS-CoV-2, influenza and respiratory syncytial virus influence epidemic timing and risk - PubMed
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- Interactions between SARS-CoV-2, influenza, and RSV influence epidemic timing and risk.
- Study analyzed weekly surveillance data from seven regions (Oct 2021–May 2024) using statistical and mechanistic models.
- Influenza A (IAV) circulation reduces SARS-CoV-2 infection risk, with lowest relative risk (0.58) at 5-week lag when IAV positivity is at 70th percentile.
- Mechanistic model shows IAV infection reduces SARS-CoV-2 infection by 94.24%, with protective effect lasting ~38 days.
- SARS-CoV-2 infection slightly increases IAV infection risk.
- Findings suggest ecological or immunological mechanisms behind virus interactions, impacting public health strategies.