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Gene therapy for sickle cell disease: Practice recommendations from the American Society for Transplantation and Cellular Therapy and the International Society for Cell & Gene Therapy - PubMed

7 hours ago
  • #clinical recommendations
  • #gene therapy
  • #sickle cell disease
  • Gene therapy is now a transformative treatment for sickle cell disease, with recent regulatory approvals.
  • The American Society for Transplantation and Cellular Therapy and the International Society for Cell & Gene Therapy provide consensus recommendations.
  • Key areas covered include patient selection, stem cell mobilization, manufacturing, conditioning, and long-term follow-up.
  • Recommendations aim to standardize clinical practice, support decision-making, and ensure safe, equitable delivery of gene therapy.