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Heparan sulfate as an attachment factor for ASFV is restricted by host HB-EGF - PubMed

4 hours ago
  • #HB-EGF
  • #African swine fever virus
  • #Heparan sulfate
  • Heparan sulfate serves as an attachment factor for African swine fever virus (ASFV).
  • Host HB-EGF restricts the role of heparan sulfate in ASFV attachment.
  • Experiments with ASFV isolates were conducted in BSL-3 facilities at Lanzhou Veterinary Research Institute (LVRI).
  • The study was approved by the Ministry of Agriculture and Rural Affairs and the China National Accreditation Service for Conformity Assessment.
  • The authors declare no competing interests.
  • References include studies on ASFV, viral attachment mechanisms, and viral transmission.