Association between C-reactive protein-triglyceride-glucose index and risk of stroke in different renal function status: a national cohort study - PubMed
2 hours ago
- #Renal Function
- #Stroke Risk
- #CTI
- The study investigates the association between the C-reactive protein-triglyceride-glucose index (CTI) and stroke risk across different renal function levels.
- A cohort of 8,808 participants aged 45+ from the China Health and Retirement Longitudinal Study (CHARLS) was analyzed from 2011 to 2018.
- CTI was calculated using CRP, triglyceride, and fasting plasma glucose levels.
- Each 1-unit increase in CTI was associated with a 15% higher stroke risk.
- A stronger association was found in individuals with mildly reduced renal function (eGFR 60-89 mL/min/1.73 m²), with the highest CTI quartile showing an HR of 2.73.
- No significant associations were observed in participants with preserved or moderately-to-severely reduced renal function.
- CTI may offer clinical value for stroke risk assessment, especially in those with mild renal impairment.