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Symptom Network Dynamics during Antipsychotic Treatment in First-Episode Psychosis - PubMed

4 hours ago
  • #psychosis
  • #antipsychotic
  • #symptom-network
  • Study examines symptom network dynamics in first-episode psychosis patients undergoing antipsychotic treatment.
  • Baseline symptom networks did not differ between remitters and non-remitters.
  • Temporal symptom networks showed significant differences between remitters and non-remitters in symptom connections and strengths.
  • Key symptoms identified varied between remitters and non-remitters.
  • No robust symptom-specific medication effects were found between amisulpride and olanzapine.
  • Temporal symptom dynamics, rather than baseline relationships, differentiate treatment response trajectories.
  • Findings suggest generic treatment mechanisms rather than antipsychotic-specific effects.