New drug therapies for hypertension - PubMed
8 days ago
- #cardiovascular
- #hypertension
- #drug-therapy
- Global blood pressure control rates remain low despite existing antihypertensive therapies.
- New drug therapies target physiological pathways beyond conventional treatments.
- Innovations include small interfering RNA agents to inhibit angiotensinogen synthesis.
- New strategies aim to selectively modulate aldosterone, including aldosterone synthase inhibitors and non-steroidal mineralocorticoid receptor antagonists.
- There is growing interest in therapies to enhance the natriuretic peptide system.
- Benefits of new therapies must be balanced against safety, cost, clinical outcomes, and equitable access.