mRNA flu vaccine is up to 34.5% more effective than current flu vaccines
20 hours ago
- #mRNA-vaccine
- #public-health
- #influenza
- mRNA flu vaccine showed 34.5% higher efficacy than standard flu vaccine in preventing lab-confirmed flu.
- The mRNA vaccine performed better against influenza A strains (H3N2 and H1N1) but had weaker protection against influenza B strains.
- Participants receiving the mRNA vaccine reported more frequent side effects like fatigue, headache, muscle pain, and fever, though mostly mild to moderate.
- The study did not include adults over 65, a high-risk group for severe flu, and showed no significant benefit for this age group in separate trials.
- mRNA vaccines offer faster production and potential for combination vaccines, but cost-effectiveness and public acceptance remain concerns.
- The trial demonstrated robust immune responses, including higher antibody levels and stronger T-cell activation against influenza A.
- Despite higher reactogenicity, the safety profile of the mRNA vaccine was acceptable, with no reported cases of myocarditis.