The global cancer crisis: a review of growing burden, deepening inequality and initiatives for prevention and early detection - PubMed
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- #health-disparities
- Cancer is a major global health crisis with over 20 million new cases and 10 million deaths annually.
- 75% of cancer deaths occur in low- and middle-income countries despite lower incidence rates.
- Lung cancer is the leading cause of cancer deaths globally, followed by breast and colorectal cancers.
- Disparities exist with high-income regions having higher incidence but lower mortality compared to low-income regions.
- Cancer deaths in low-income countries are projected to increase by 155% by 2050 compared to 56% in high-income nations.
- 56% of cancer patients worldwide face catastrophic health expenditures, with higher rates in low-income countries.
- Prevention strategies can significantly reduce cancer burden, including targeting infectious and lifestyle-related cancers.
- Emerging genetic technologies like universal testing and pharmacogenomics offer new prevention and treatment opportunities.
- The primary barrier to reducing cancer burden is systematic implementation of known prevention strategies.
- Governments and policymakers need clearer evidence and education to motivate action against cancer.